The maternal mortality rate is an important indicator that shows a country's ability to deal with existing health conditions. The reduction in MMR as a global focus can be supported through the realization of quality and sustainable antenatal care services. This study aims to analyze the determinants of ANC in pregnant women in healthcare facilities during the Covid-19 pandemic. Articles are written based on data compilation through a systematic review method using several databases such as ProQuest, Science Direct, Pubmed, SAGE and Google Scholar. selected based on PRISMA guidelines and inclusion criteria, there were 9 articles that met the criteria and were selected for further analysis to answer the research objectives. The main findings stated that age, maternal anxiety about the pandemic, pregnancy condition, delivery history, compliance, education level, employment level, attitude, knowledge, husband's support, and access to healthcare facilities were determinants of ANC in pregnant women in healthcare facilities during the Covid-19 pandemic.